The use of Artificial Intelligence in Parkinson’s Disease

Authors

DOI:

https://doi.org/10.33448/rsd-v14i1.48011

Keywords:

Artficial Intelligence, Parkinson's Disease, Diagnosis, Treatment.

Abstract

Parkinson's disease (PD) is a neurological disorder that degrades the substantia nigra of the brain, causing motor deficits in the individual. Its diffuse symptoms affect clinical analysis, making early diagnosis and treatment difficult. The objective of this study is to analyze the use of artificial intelligence in the diagnosis and treatment of Parkinson's disease. The methodology used was an integrative literature review based on articles published between 2019 and 2024. Significant advances were identified in using machine learning (ML) algorithms for early diagnosis, symptom monitoring, and treatment personalization. Techniques such as convolutional neural networks, biomarker analysis, Internet of Things (IoT) devices, computer-assisted diagnosis (CAD), and WGCNA stood out for their accuracy and efficiency in recognizing PD patterns. Although AI shows great potential in this diagnosis and monitoring, advances in treatment remain limited. Considering the topic's relevance, the development of additional studies for integrating these technologies into clinical practice is indicated.

Downloads

Download data is not yet available.

References

Anima. (2014). Manual revisão bibliográfica sistemática integrativa: a pesquisa baseada em evidências. Grupo Anima.

https://biblioteca.cofen.gov.br/wp-content/uploads/2019/06/manual_revisao_bibliografica-sistematica-integrativa.pdf.

Calderone, A. et al. (2024). Towards Transforming Neurorehabilitation: The Impact of Artificial Intelligence on Diagnosis and Treatment of Neurological Disorders. Biomedicines. 12(10), 2415.

Crossetti, M. G. M. (2012). Revisión integradora de la investigación en enfermería el rigor científico que se le exige. Rev. Gaúcha Enferm. 33(2): 8-9.

Dennisa, A-G. P. & Strafella, A. P. (2024). The Role of AI and Machine Learning in the Diagnosis of Parkinson’s Disease and Atypical Parkinsonisms. Parkinsonism & related disorders (Online)/Parkinsonism & related disorders. 106986–106986.

Dong, B.. Liu, X. & Yu, S. (2024). Utilizing machine learning algorithms to identify biomarkers associated with diabetic nephropathy: A review. Medicine. 103(8), e37235–e37235.

Faouzi, J., Colliot, O. & Corvol, J-C. (2023). Machine Learning for Parkinson’s Disease and Related Disorders. Neuromethods. 847–77.

Giannakopoulou, K-M., Roussaki, I. & Demestichas, K. (2022). Internet of Things Technologies and Machine Learning Methods for Parkinson’s Disease Diagnosis, Monitoring and Management: A Systematic Review. Sensors. 22(5), 1799.

Hughes, G. L. et al. (2020). Machine learning discriminates a movement disorder in a zebrafish model of Parkinson’s disease. Disease Models & Mechanisms. 13(10), dmm045815.

Kriegeskorte, N. & Golan, T. (2019). Neural network models and deep learning. Current Biology. 29(7), R231–R236.

Landers, M., Saria, S. & Espay, A.J. (2021). Will Artificial Intelligence Replace the Movement Disorders Specialist for Diagnosing and Managing Parkinson’s Disease? Journal of Parkinson’s Disease. 11(s1), S117–S122.

Langfelder, P., Horvath, S. (2008). WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics. 9 (1).

https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-9-559

Loh, H. W. et al. (2021). Application of Deep Learning Models for Automated Identification of Parkinson’s Disease: A Review (2011–2021). Sensors. 21 (21), 7034.

Mattos, P. C. (2015). Tipos de revisão de literatura. Unesp, 1-9. https://www.fca.unesp.br/Home/Biblioteca/tipos-de-evisao-de-literatura.pdf.

Melo, L.M., Barbosa, E.R. & Caramelli, P. (2007). Declínio cognitivo e demência associados à doença de Parkinson: características clínicas e tratamento. Archives of Clinical Psychiatry - Revista de Psiquiatria Clínica. 34(4), 176-83.

Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Editora UAB/NTE/UFSM.

Perju-Dumbrava, L. et al. (2022). Artificial intelligence applications and robotic systems in Parkinson’s disease (Review). Experimental and Therapeutic Medicine. 23(2), 153.

Rosa, C. M., Souza, P. A. R. & Silva, J. M. (2020). Inovação em saúde e internet das coisas (IoT): Um panorama do desenvolvimento científico e tecnológico. Perspectivas em Ciência da Informação. 25(3), 164–81.

Sponchiado, G. S. (2019). Estratégia de caracterização de sinais eletromiográficos baseada em redes neurais artificiais para sistemas de controle de máquinas de movimento contínuo. Dissertação (Mestrado em Engenharia Elétrica) - Escola Politécnica da Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre.

Sturchio, A. et al. Phenotype-Agnostic Molecular Subtyping of Neurodegenerative Disorders: The Cincinnati Cohort Biomarker Program (CCBP). Frontiers in Aging Neuroscience, v. 12, 8 out. 2020.

Tabashum, T. et al. (2024) Machine Learning Models for Parkinson Disease: Systematic Review. JMIR Medical Informatics, 12, e50117–e50117.

Tolosa, E. et al. (2021) Challenges in the diagnosis of Parkinson’s disease. The Lancet Neurology, 20(5), 385–397.

Vatansever, S. et al. (2020). Artificial intelligence and machine learning‐aided drug discovery in central nervous system diseases: State‐of‐the‐arts and future directions. Medicinal Research Reviews. 41 (3), 1427–73.

Vilela Jr., G. B. et al. (2023). Inteligência artificial e reabilitação neuro motora. Revista CPAQV - Centro de Pesquisas Avançadas em Qualidade de Vida. 15 (3). https://doi.org/10.36692/V15N3-30R.

Wu, P. et al. (2023). The advantages of artificial intelligence-based gait assessment in detecting, predicting, and managing Parkinson’s disease. Front Aging Neurosci. 12 (15): 1191378. DOI: 10.3389/fnagi.2023.1191378..

Yu, S. et al. (2018). Motion Sensor-Based Assessment on Fall Risk and Parkinson’s Disease Severity: A Deep Multi-Source Multi-Task Learning (DMML) Approach. Annals of the 2018 IEEE International Conference. 9, 174–9 10.1109/ICHI.2018.00027. https://ieeexplore.ieee.org/document/8419360/.

Published

2025-01-20

Issue

Section

Review Article

How to Cite

The use of Artificial Intelligence in Parkinson’s Disease. Research, Society and Development, [S. l.], v. 14, n. 1, p. e7214148011, 2025. DOI: 10.33448/rsd-v14i1.48011. Disponível em: https://ojs34.rsdjournal.org/index.php/rsd/article/view/48011. Acesso em: 28 jun. 2025.