Epidemiological profile of patients undergoing endoscopic retrograde cholangiopancreatography in a reference service in Pará
DOI:
https://doi.org/10.33448/rsd-v14i1.48100Keywords:
Endoscopic Retrograde Cholangiopancreatography, Bile ducts, Choledocholithiasis.Abstract
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a minimally invasive procedure that combines endoscopy and fluoroscopy and is widely used for the diagnosis and treatment of pathologies of the biliary and pancreatic systems. Although efficient, it presents risks such as pancreatitis, hemorrhage, and perforation, which justifies the need for epidemiological monitoring and evaluation of clinical outcomes. The objective of this study was to analyze the epidemiological profile and clinical outcomes of patients undergoing ERCP in a referral hospital in Pará in 2024. For this purpose, a prospective, descriptive, and quantitative study was carried out, including 37 patients over 18 years of age, of both sexes, who agreed to participate in the study. Demographic, clinical, and procedure-related data were collected using standardized forms. Statistical analyses were performed using Excel and Epi Info BioEstat 5.0 programs. The results showed a predominance of women (70.27%) and patients over 60 years of age (37.84%). Regarding comorbidities, 56.76% of patients were healthy, while arterial hypertension was the most frequent condition (21.62%). The main indications for ERCP were cholestatic syndrome (64.86%) and choledocholithiasis (29.73%). The success rate in biliary cannulation was 89.19% and stone removal represented 69.7% of the therapies performed. The incidence of labor complications (8.11%) was similar to that reported in other studies (4-10%), confirming the relative safety of the procedure when well performed. Finally, the findings corroborate the national and international literature on the prevalence of choledocholithiasis in women and the elderly, in addition to the efficacy of ERCP as a therapeutic method.
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Antonello, G. M. (2020). Análise do perfil de pacientes submetidos à colangiopancreatografia retrógrada endoscópica em um centro de tratamento quaternário (Trabalho de conclusão de curso, Instituto Nacional de Câncer José Alencar Gomes da Silva). Instituto Nacional de Câncer José Alencar Gomes da Silva. https://ninho.inca.gov.br/jspui/handle/123456789/2212
Bang, J. Y., Wilcox, C. M., Navaneethan, U., Hawes, R., & Varadarajulu, S. (2024). Orlando Protocol for Single Session Ductal Clearance of Common Bile Duct Stones at Endoscopic Retrograde Cholangiopancreatography. Dig Endosc. 36 (7), 825-833. DOI: 10.1111/den.14719
Barakat, M. T., Girotra, M., Huang, R .J. et al. (2021). Goff Septotomy Is a Safe and Effective Salvage Biliary Access Technique Following Failed Cannulation at ERCP. Dig Dis Sci.66 (3), 866-872. doi:10.1007/s10620-020-06124-6
Baron, T.H., Kozarek, R.A., & Carr-Locke, D. L. (2019). ERCP. (3. ed. rev. e ampl.). Philadelphia: Elsevier. https://shop.elsevier.com/books/ercp/baron/978-0-323-48109-0
Borges, A. C., et al. (2018). Performance de CPRE em centro terciário brasileiro: Foco em novos fatores de risco, complicações e indicadores de qualidade. ABCD, Arquivos Brasileiros de Cirurgia Digestiva. 31(1), e1348. https://doi.org/10.1590/0102-672020180001e1348
Canbak, T., Acar, A., Basak, F.,Ozdil, K., Bas, G., & Unal, E. (2019). Risk factors for complications after endoscopic retrograde cholangiopancreatography: A referral center experience. Annali Italiani di Chirurgia, 90, 520-523. https://pubmed.ncbi.nlm.nih.gov/31541544/
Castro F, Aponte N, & Díaz M. (2022). Comorbilidades en pacientes sometidos a CPRE: análisis de 5 años en un centro terciario. Revista Colombiana de Gastroenterología. 37(2), 87-95.
Chathadi, K. V., Fanelli, R. D., Fisher, D. A., Foley, K., Fonkalsrud, L., Hwang, J. H., Jue, T. L., Khashab, M. A., Lightdale, J. R., Muthusamy, V. R., Pasha, F. F., Saltzman, J. R., Sharaf, R., Shaukat, A., Shergill, A. K., Wang, A., Cash, B. D., & DeWitt, J. M. (2015). ASGE guideline: The role of ERCP in benign diseases of the biliary tract. Gastrointestinal Endoscopy, 81(4), 795-803. doi: 10.1016/j.gie.2014.11.019
Comissão Nacional de Incorporação de Tecnologias no SUS- CONITEC. (2019). Colangiopancreatografia endoscópica retrógrada pré cirúrgica no tratamento de coledocolitíase. Brasília: Ministério da Saúde; Relatório, 471.
Jeurnink, S. M., et al. (2011). Predictors of complications after endoscopic retrograde cholangiopancreatography: A prognostic model for early discharge. Surgical Endoscopy, 25(9), 2892–2900. doi: 10.1007/s00464-011-1638-9
Johnson, K. D., et al. (2020). Endoscopic retrograde cholangiopancreatography-related complications and their management strategies: A "scoping" literature review. Digestive Diseases and Sciences, 65(2), 361–375. https://doi.org/10.1007/s10620-019-05970-3
Lima, A. M., et al. (2023). Colangiografia retrógrada endoscópica (CPRE): Análise das indicações e complicações no Hospital Universitário Presidente Dutra. Brazilian Journal of Health Review. https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/58106/42365
Lyu, Y., et al. (2022). Impact of the Timing of Endoscopic Retrograde Cholangiopancreatography for the Treatment of Acute Cholangitis: a meta-analysis and systematic review. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. 32 (6), 764-769. http://dx.doi.org/10.1097/sle.0000000000001110
Martínez-Pérez, A., & García-Santos, P. (2023). Complicaciones post-CPRE: factores de riesgo y manejo clínico. Revista Latinoamericana de Endoscopia Digestiva. 25(3), 145-153.
Morales, S. J., Sampath, K., & Gardner, T. B. (2018). A review of prevention of post-ERCP pancreatitis. Gastroenterology & hepatology, 14(5), 286. https://pmc.ncbi.nlm.nih.gov/articles/PMC6034611/
Park, C. H., et al. (2018). Aggressive intravenous hydration with lactated Ringer's solution for prevention of post-ERCP pancreatitis: A prospective randomized multicenter clinical trial. Endoscopy, 50(4), 378–385. https://doi.org/10.1055/s-0043-122386
Pereira, A. S. et al. (2018). Metodologia da pesquisa Cientifica. Editora UAB/NTE/UFSM. https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1
Ramai D, Smit E, Kani H T, et al. Cannulation Rates and Technical Performance Evaluation of Commercially Available Single-Use Duodenoscopes for Endoscopic Retrograde Cholangiopancreatography: A Systematic Review and Meta-Analysis. Dig Liver Dis. 2024;56(1), 123-129. doi:10.1016/j.dld.2023.02.022
Rohde, L.; & Osvaldt, A. B. (2018) Rotinas em cirurgia digestiva. Organizadores, Luiz Rohde ; Alessandro Bersch Osvaldt. (3. ed.). Editora Artmed.
Tringali, A., et al. (2021). Endoscopic retrograde cholangiopancreatography: Indications, patient preparation, and complications. UpToDate, https://www.uptodate.com/online
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