Opportunist infections in patients with Crohn's Disease and Ulcerative Colitis: A current integrative review
DOI:
https://doi.org/10.33448/rsd-v14i3.48467Keywords:
Opportunistic infections, Crohn's disease, Ulcerative colitis.Abstract
Objectives: Conduct a literature review on the most common opportunistic infections in patients with Crohn's Disease and Ulcerative Colitis. Methodology: This research focuses on an integrated literature review. The integrative review (IR) method allows for a greater sense of understanding by employing a systematic and rigorous process. Results: Thus, a total of 13 articles were discovered in the VHL database, while 42 papers were discovered in the Medline database via PubMed, totaling 55 publications. The final sample consisted of 8 articles, all belonging to the Medline database via PubMed after applying the inclusion and exclusion criteria. Conclusion: It is considered extremely important to examine all available evidence on occult infections in patients with Crohn's disease and ulcerative colitis, as it will allow patients and the health professionals who care for them to respond and act appropriately in order to preserve their quality of life and ensure that their treatments are effective.
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References
Azevedo, K. P., et al. (2022). Probiotics in Crohn's disease remission: a systematic review. Archivos Latinoamericanos de Nutrición, 72(1), 50-59.
Barnes, E. L. (2020). Infecções oportunistas e oportunidades de ação. Inflammatory Bowel Diseases, 26(2), 301-303.
Botelho, L. L. R., Cunha, C. C. A. & Macedo, M. (2011). O método da revisão integrativa nos estudos organizacionais. Gestão E Sociedade. 121-36. https://doi.org/10.21171/ges.v5i11.1220.
Cambui, Y. R. S., & Natali, M. R. M. (2015). Doenças inflamatórias intestinais: revisão narrativa da literatura. Revista da Faculdade de Ciências Médicas de Sorocaba, 17(3), 116-119.
Ciccocioppo, R., Racca, F., Paolucci, S., Campanini, G., Pozzi, L., Betti, E., et al. (2015). Infecção por citomegalovírus humano e vírus Epstein-Barr na doença inflamatória intestinal: necessidade de medição da carga viral da mucosa. World Journal of Gastroenterology, 21(6), 1915-1926. https://doi.org/10.3748/wjg.v21.i6.1915
Colombel, J. F., D'Haens, G., Lee, W. J., Petersson, J., & Panaccione, R. (2020). Resultados e estratégias para apoiar uma abordagem de tratamento para o alvo na doença inflamatória intestinal: uma revisão sistemática. Journal of Crohn's and Colitis, 14, 254-266.
Craviotto, F. P., Bresciani, G., Pugliese, D., & Parisi, G. (2021). Viral infections in inflammatory bowel disease: Tips and tricks for correct management. World Journal of Gastroenterology, 27(23), 3953-3964. https://doi.org/10.3748/wjg.v27.i23.3953.
Crossetti, M. G. M. (2012). Revisión integradora de la investigación en enfermería el rigor científico que se le exige. Maria Da Graça Oliveira Crossetti. Rev. Gaúcha Enferm. 33 (2): 8-9.
Da Silva Venito, L., Santos, M. S. B., & Ferraz, A. R. (2022). Doença de Crohn e retocolite ulcerativa. Revista Eletrônica Acervo Saúde, 15(7), e10667.
Ford, A. C., & Peyrin-Biroulet, L. (2013). Infecções oportunistas com terapia de fator de necrose antitumoral-α em doença inflamatória intestinal: meta-análise de ensaios controlados randomizados. American Journal of Gastroenterology, 108, 1268-1276. https://doi.org/10.1038/ajg.2013.138
Gonçalves, M. M., et al. (2022). A doença de Crohn em decorrência da desregulação do sistema imunológico. RECIMA21 – Revista Científica Multidisciplinar, 3(8), e381844.
Hissong, B. D., Chen, L., & Yantiss, R. K. (2019). Cytomegalovirus reactivation in inflammatory bowel disease: An uncommon occurrence related to corticosteroid dependence. Modern Pathology, 32(7), 1010-1017. https://doi.org/10.1038/s41379-019-0177-3.
Kawai, K., & Bocejo, B. P. (2017). Fatores de risco para herpes zoster: uma revisão sistemática e metanálise. Mayo Clinic Proceedings, 92, 1806-1821.
Kochar, B., Dhere, T., & Parikh, N. D. (2020). Pretreatment frailty is independently associated with increased risk of infections after immunosuppression in patients with inflammatory bowel diseases. Gastroenterology, 158(5), 1306-1316. https://doi.org/10.1053/j.gastro.2019.11.300.
Lai, W. L., Chen, Y. H., & Chou, L. F. (2021). The incidence rate of herpes zoster in inflammatory bowel disease: A meta-analysis of cohort studies. Medicine, 100(17), e25758. https://doi.org/10.1097/MD.0000000000025758.
Loftus, W. Jr., & EV, A. (2009). Perfil de segurança da terapêutica para DII: riscos infecciosos. Gastroenterology Clinics of North America, 38, 691-709.
Mendes, K. D. S., Silveira, R. C. C. P., & Galvão, C. M. (2008). Revisão integrativa: Método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & Contexto Enfermagem, 17(4), 758-764. https://doi.org/10.1590/S0104-07072008000400018.
Moraes-Pinto, M. I., & Ferrarini, M. A. G. (2020). Infecções oportunistas em pediatria: quando suspeitar e como abordar. Jornal de Pediatria, 96, 47-57.
Mushtaq, K., Khan, Z., Aziz, M., Alyousif, Z. A., Siddiqui, N., Khan, M. A., & Nawras, A. (2020). Trends and outcomes of fungal infections in hospitalized patients of inflammatory bowel disease: A nationwide analysis. Translational Gastroenterology and Hepatology, 5, 35. https://doi.org/10.21037/tgh.2019.10.14.
Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Santa Maria/RS. Ed. UAB/NTE/UFSM.
Revoredo, C. M. S., et al. (2017). Doença de Crohn e probióticos: uma revisão. Revista da Associação Brasileira de Nutrição, 8(2), 67-73.
Santos, A. L. C., et al. (2021). Terapias nutricionais nas doenças inflamatórias intestinais: Doença de Crohn e Retocolite Ulcerativa. Research, Society and Development, 10(7), e11410716660.
Sheriff, M. Z., et al. (2020). Opportunistic infections are more prevalent in Crohn’s disease and ulcerative colitis: a large population-based study. Inflammatory Bowel Diseases, 26(2), 291-300.
Snyder, H. (2019). Literature review as a research methodology: An overview and guidelines. Journal of business research, 104, 333-339.
Stamatiades, G. A., Ioannou, P., Petrikkos, G., & Tsioutis, C. (2018). Fungal infections in patients with inflammatory bowel disease: A systematic review. Mycoses, 61(6), 366–376. https://doi.org/10.1111/myc.12753.
Wandekoken, K. G. (2019). Epidemiologia da doença inflamatória intestinal no Brasil (Monografia). Universidade Federal do Espírito Santo. Disponível em: https://residenciamedica.ufes.br/sites/residenciamedica.ufes.br/files/field/anexo/tcc_pronto_kethleen_gomes_wandekoken.pdf
Zaltman, C. (2007). Doença inflamatória intestinal: qual a relevância da doença no Brasil? Cadernos de Saúde Pública, 23, 992-993.
Zhang, H., Zhao, S., & Cao, Z. (2022). Impact of Epstein–Barr virus infection in patients with inflammatory bowel disease. Frontiers in Immunology, 13, 1001055. https://doi.org/10.3389/fimmu.2022.1001055.
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Copyright (c) 2025 Carla Maria Zanelli Pinaty; Amanda Pimpim Capistrano Martins; Juliana Dourado de Araújo Costa; Karoline Danielle Silva de Jesus; Maria Eduarda Miranda Sansão; Pedro Eduardo Barros Barbosa

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