Staphylococcal scalded skin syndrome in an infant: Case report
DOI:
https://doi.org/10.33448/rsd-v14i6.48902Keywords:
Staphylococcal Scalded Skin Syndrome, Skin Diseases, Staphylococcus aureus.Abstract
The aim of this article is to present a case study of the rapid diagnosis of scalded skin syndrome in order to establish appropriate treatment and reduce the risk of complications arising from the syndrome. Scalded skin syndrome is an infection predominantly caused by Staphylococcus aureus, resulting from the hematogenous dissemination of exotoxins to the skin, causing detachment of the granulosa zone of the epidermis. Therefore, its destruction and exfoliation of the skin in a localized or generalized way. It is important to emphasize that the infectious focus is far from the release of the exotoxin through inflammation. It mainly affects children under five years of age, but can occur in adolescents and adults with an underlying disease. In this case, this is a male patient, 1 year old, black, presenting with spots on the skin associated with fever, which progressed to hyperemia and blisters on the trunk, upper limbs and face. With a pathological history of pharyngitis in the week before the clinical presentation, amoxicillin was administered. After medical evaluation, he was diagnosed and began intravenous treatment with Ceftriaxone and Oxalicin, in addition to dermatological care. After 10 days of hospital treatment, he was discharged and progressed without scars.
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Basurto, C., Baah-Owusu, N., & Berreth, K. (2023). Recurrent staphylococcal scalded skin syndrome in a 20-month-old: A case report. Clinical Case Reports, 11(8), e7805.
Brazel, M., Desai, A., Are, A., & Motaparthi, K. (2021). Staphylococcal scalded skin syndrome and bullous impetigo. Medicina, 57(11), 1157. https://doi.org/10.3390/medicina57111157
Cleonice de Souza, F., Feilstrecker, S., & Barros Hubner, I. (2015). Síndrome da pele escaldada: Relato de caso. Boletim Científico de Pediatria, 4(2), 49–51.
Fernández-Fructuoso, J., Sevilla-Denia, S., & Lloreda García , J. (2022). Staphylococcal scalded skin syndrome in a newborn. European Journal of Pediatric Dermatology, 32(3), 151-153.
Grama, A., Marginean, O. C., Melit, L. E., & Georgescu, A. M. (2016). Staphylococcal scalded skin syndrome in child. A case report and a review from literature. The Journal of Critical Care Medicine, 2(4), 192–197. https://doi.org/10.1515/jccm-2016-0028
Gray, L., Olson, J., Brintz, B. J., & Cipriano, S. D. (2022). Staphylococcal scalded skin syndrome: Clinical features, ancillary testing, and patient management. Pediatric Dermatology, 39(6), 908–913.
Jameson, J. L., Fauci, A. S., Kasper, D. L., Hauser, S. L., & Longo, D. L. (Eds.). (2024). Staphylococcal scalded skin syndrome. In Harrison’s Principles of Internal Medicine (21st ed.). UpToDate. https://www.uptodate.com.
Jordan, K. S. (2019). Staphylococcal scalded skin syndrome. Advanced Emergency Nursing Journal, 41(2), 129–134. https://doi.org/10.1097/tme.0000000000000235
Kaya, A., Uğur, M., Seyman, D., Seyman, H., & Kılıç, A. (2025). Investigation of staphylococcal scalded skin syndrome outbreak in neonatal intensive care unit using whole genome sequencing. American Journal of Infection Control. Advance online publication. https://doi.org/10.1016/j.ajic.2024.04.084
K Mishra, A., Yadav, P., & Amrita Mishra, A. (2016). A systemic review on staphylococcal scalded skin syndrome (SSSS): A rare and critical disease of neonates. The Open Microbiology Journal, 10, 150–159.
Mazori, D. R., Leonard, A., Alexander, J. B., & Glick, S. A. (2020). The spectrum of staphylococcal scalded skin syndrome: A case series in children. Clinical and Experimental Dermatology, 45(3), 333–336. https://doi.org/10.1111/ced.14116
Medeiros, R. S., & Silva, A. L. (2020). Síndrome da pele escaldada estafilocócica: relato de caso. Revista Dédalo, 20(2), 1–10.
Patel, G. K., & Ford, J. B. (2023). Staphylococcal Scalded Skin Syndrome. In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK448135/
Pereira, A. L. dos S., Moraes, P. G. dos S. de, Barros, C. F. E. de, Alves, J. de L., Bezerra, A. M., Souza, F. R. de, Anjos, C. V. O. dos, Teixeira, W. S., & Costa, W. K. (2024). Patogênese de Staphylococcus aureus: O papel das toxinas na infecção e disseminação. Revista Eletrônica em Estágio e Pesquisa em Educação e Saúde – REER, 11(2), 231–240.
Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Editora UAB/NTE/UFSM.
Ross, A., Saleh, H. M., & Sathe, N. C. (2025). Staphylococcal Scalded Skin Syndrome. In StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK448135/
Rouva, G., Vergadi, E., Krasagakis, K., & Galanakis, E. (2025). Understanding host’s response to staphylococcal scalded skin syndrome. Acta Paediatrica, 114(2), 241–247.
Santos Veiga do Carmo, R. (2022). Síndrome da pele escaldada estafilocócica: Relato de caso. Revista De Medicina, 101(6).
Sugimoto, S., Iwamoto, T., Takemoto, A., Okada, H., Tajima, T., & Mizunoe, Y. (2014). Nosocomial outbreak of staphylococcal scalded skin syndrome in neonates: Molecular typing of methicillin-susceptible Staphylococcus aureus by pulsed-field gel electrophoresis and whole-genome sequencing. Journal of Clinical Microbiology, 52(3), 881–884.
Toassi, R. F. C. & Petry, P. C. (2021). Metodologia científica aplicada à área da Saúde. (2ed.). Editora da UFRGS.
Vidotto, V. M. (2023). Análises moleculares e estratégias para a inibição do processo de reconhecimento e clivagem da Desmogleína 1 pela toxina esfoliativa A (ETA) de Staphylococcus aureus [Dissertação de mestrado, Universidade Estadual Paulista “Júlio de Mesquita Filho”]. Repositório Institucional da UNESP.
Wang, Z., Feig, J. L., Mannschreck, D. B., & Cohen, B. A. (2019). Antibiotic sensitivity and clinical outcomes in staphylococcal scalded skin syndrome. Pediatric Dermatology, 37(1), 222–223. https://doi.org/10.1111/pde.14014
Yin, R.K. (2015). O estudo de caso. Editora Bookman.
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Copyright (c) 2025 Amanda Santana de Medeiros Dalla Pria; Bruna Carvalho Botelho; Bruna Gonzatti Batista; Gabryela Silveira de Lima Eleutério; Mariana Fonseca Meireles; Nathalia Ferreira Souza; Thaís Pereira Martins

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